Latest & greatest articles for type 2 diabetes

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Top results for type 2 diabetes

1861. Tomato juice and platelet aggregation in type 2 diabetes. (Abstract)

Tomato juice and platelet aggregation in type 2 diabetes. 15315994 2004 08 23 2016 10 17 1538-3598 292 7 2004 Aug 18 JAMA JAMA Tomato juice and platelet aggregation in type 2 diabetes. 805-6 Lazarus Sheryl A SA Bowen Kerry K Garg Manohar L ML eng Clinical Trial Letter Randomized Controlled Trial United States JAMA 7501160 0098-7484 0 Blood Glucose AIM IM Adult Aged Aged, 80 and over Beverages Blood Glucose Cardiovascular Diseases prevention & control Diabetes Mellitus, Type 2 blood diet therapy (...) Diabetic Angiopathies prevention & control Female Humans Lycopersicon esculentum Male Middle Aged Platelet Aggregation 2004 8 19 5 0 2004 8 24 5 0 2004 8 19 5 0 ppublish 15315994 10.1001/jama.292.7.805 292/7/805

2004 JAMA Controlled trial quality: uncertain

1862. Training in flexible intensive insulin management improved glycaemic control and quality of life in type 1 diabetes Full Text available with Trip Pro

glycaemic control and quality of life in patients with type 1 diabetes? Design Randomised (allocation concealed), unblinded, controlled trial with follow up at 6 months (Dose Adjustment for Normal Eating [DAFNE] trial). Setting 3 hospital diabetes clinics in Sheffield, Northumbria, and London, UK. Patients 169 patients >18 years of age with clinical features of type 1 diabetes, moderate or poor glycaemic control (glycated haemoglobin [HbA 1c ] 7.5–12%), and duration of diabetes >2 years without advanced (...) is not relevant to patients with type 2 diabetes because of differences in the management of the diseases. Type 1 diabetes is an insulin deficiency disorder requiring insulin replacement. Type 2 diabetes requires dietary manipulation and lifestyle changes (eg, eating behaviour and activity levels) to achieve good glycaemic control. Promoting dietary freedom in this context is probably not desirable! However, the 1% reduction in HbA 1c achieved in the DAFNE trial is desirable for people with both types

2004 Evidence-Based Nursing

1863. Best practice guideline for the subcutaneous administration of insulin in adults with type 2 diabetes.

Best practice guideline for the subcutaneous administration of insulin in adults with type 2 diabetes. Guidelines and Measures | Agency for Healthcare Research & Quality HHS.gov Search ahrq.gov Search ahrq.gov Menu Topics A - Z Healthcare Delivery Latest available findings on quality of and access to health care Searchable database of AHRQ Grants, Working Papers & HHS Recovery Act Projects AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund You are here Guidelines

2004 Registered Nurses' Association of Ontario

1864. Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents. (Abstract)

Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents. The development of type 1 diabetes mellitus is preceded by autoimmunity against islet beta cells.To determine the risk for islet autoimmunity and childhood diabetes in offspring of affected parents.Prospective cohort study.German BABYDIAB study.1610 offspring of parents with type 1 diabetes.Autoantibodies to islet autoantigens were measured at 9 months, 2 years, 5 (...) positive by age 2 years (P < 0.001), and progression to diabetes was inversely related to the age of positivity for multiple autoantibodies (P = 0.02).The findings are limited to childhood diabetes in affected families.Childhood autoimmune diabetes is associated with autoimmunity that starts before 2 years of age.

2004 Annals of Internal Medicine

1865. Primary prevention of type 2 diabetes mellitus by lifestyle intervention: implications for health policy. (Abstract)

Primary prevention of type 2 diabetes mellitus by lifestyle intervention: implications for health policy. More than 18 million Americans currently have diabetes mellitus. The economic and human cost of the disease is devastating. In the United States, diabetes is the most common cause of blindness among working-age adults, the most common cause of nontraumatic amputations and end-stage renal disease, and the sixth most common cause of death. For the cohort of Americans born in 2000 (...) , the estimated lifetime risk for diabetes is more than 1 in 3. In the next 50 years, the number of diagnosed cases of diabetes is predicted to increase by 165% in the United States, with the largest relative increases seen among African Americans, American Indians, Alaska Natives, Asian and Pacific Islanders, and Hispanic/Latino persons. Compelling scientific evidence indicates that lifestyle change prevents or delays the occurrence of type 2 diabetes in high-risk groups. This body of evidence from

2004 Annals of Internal Medicine

1866. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study. Full Text available with Trip Pro

Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study. To evaluate baseline predictors for the development of persistent microalbuminuria and macroalbuminuria prospectively in patients with type 1 diabetes.Prospective observational study of an inception cohort.Outpatient diabetic clinic in a tertiary referral centre, Gentofte, Denmark.286 patients (216 adults) newly diagnosed with type 1 diabetes consecutively admitted (...) = 13).Around one third of patients newly diagnosed with type 1 diabetes develop persistent microalbuminuria within the first 20 years of diabetes. Several potentially modifiable risk factors predict the development of persistent microalbuminaria and persistent macroalbuminuria.

2004 BMJ

1867. Screening for type 2 diabetes mellitus: a cost-effectiveness analysis. (Abstract)

Screening for type 2 diabetes mellitus: a cost-effectiveness analysis. No randomized, controlled trial of screening for diabetes has been conducted. In the absence of direct evidence, cost-effectiveness models may provide guidance about preferred screening strategies.To estimate the incremental cost-effectiveness of 2 diabetes screening strategies: screening targeted to people with hypertension and universal screening.Markov model.United Kingdom Prospective Diabetes Study, Hypertension Optimal (...) for stroke attributable to intensive hypertension control.We did not consider screening targeted to persons with dyslipidemia, and we used studies of people whose diabetes was detected clinically to estimate screening benefits.Diabetes screening targeted to people with hypertension is more cost-effective than universal screening. The most cost-effective strategy is targeted screening at age 55 to 75 years.

2004 Annals of Internal Medicine

1868. Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. Full Text available with Trip Pro

Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. Endothelial dysfunction occurs in diagnosed type 2 diabetes mellitus but may also precede development of diabetes.To determine whether elevated plasma levels of biomarkers reflecting endothelial dysfunction (E-selectin; intercellular adhesion molecule 1 [ICAM-1]; and vascular cell adhesion molecule 1 [VCAM-1]) predict development of type 2 diabetes in initially nondiabetic women.Prospective, nested case-control study (...) within the Nurses' Health Study, an ongoing US study initiated in 1976.Of 121 700 women initially enrolled, 32 826 provided blood samples in 1989-1990; of those free of diabetes, cardiovascular disease, or cancer at baseline, 737 developed incident diabetes by 2000. Controls (n = 785) were selected according to matched age, fasting status, and race.Risk of confirmed clinically diagnosed type 2 diabetes by baseline levels of E-selectin, ICAM-1, and VCAM-1.Baseline median levels of the biomarkers were

2004 JAMA

1869. Lipid control in the management of type 2 diabetes mellitus: a clinical practice guideline from the American College of Physicians. (Abstract)

Lipid control in the management of type 2 diabetes mellitus: a clinical practice guideline from the American College of Physicians. In an effort to provide internists and other primary care physicians with effective management strategies for diabetes care, the Clinical Efficacy Assessment Subcommittee (CEAS) of the American College of Physicians (ACP) decided to develop guidelines on the management of dyslipidemia, particularly hypercholesterolemia, in people with type 2 diabetes mellitus (...) . The CEAS commissioned a systematic review of the currently available evidence on the management of lipids in type 2 diabetes mellitus. The evidence review is presented in a background paper in this issue. On the basis of this systematic review, the CEAS developed recommendations that the ACP Board of Regents then approved as policy. The target audience for this guideline is all clinicians who care for patients with type 2 diabetes. The target patient population is all persons with type 2 diabetes

2004 Annals of Internal Medicine

1870. Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands. Full Text available with Trip Pro

Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands. To investigate maternal, perinatal, and neonatal outcomes of pregnancies in women with type 1 diabetes in the Netherlands.Nationwide prospective cohort study.All 118 hospitals in the Netherlands.323 women with type 1 diabetes who became pregnant between 1 April 1999 and 1 April 2000.Maternal, perinatal, and neonatal outcomes of pregnancy.84% (n = 271) of the pregnancies were (...) , maternal and perinatal complications were still increased in women with type 1 diabetes. Neonatal morbidity, especially hypoglycaemia, was also extremely high. Near optimal maternal glycaemic control (HbA1c < or = 7.0%) apparently is not good enough.

2004 BMJ

1871. Childhood vaccination and type 1 diabetes. Full Text available with Trip Pro

Childhood vaccination and type 1 diabetes. A link between childhood vaccinations and the development of type 1 diabetes has been proposed.We evaluated a cohort comprising all children born in Denmark from January 1, 1990, through December 31, 2000, for whom detailed information on vaccinations and type 1 diabetes was available. Using Poisson regression models, we estimated rate ratios according to vaccination status, including the trend associated with the number of doses, among all children (...) and in a subgroup of children who had siblings with type 1 diabetes. Given recent claims of clustering of cases of diabetes two to four years after vaccination, we also estimated rate ratios during the period after vaccination.Type 1 diabetes was diagnosed in 681 children during 4,720,517 person-years of follow-up. The rate ratio for type 1 diabetes among children who received at least one dose of vaccine, as compared with unvaccinated children, was 0.91 (95 percent confidence interval, 0.74 to 1.12

2004 NEJM

1872. Coffee consumption and risk of type 2 diabetes mellitus among middle-aged Finnish men and women. Full Text available with Trip Pro

Coffee consumption and risk of type 2 diabetes mellitus among middle-aged Finnish men and women. Only a few studies of coffee consumption and diabetes mellitus (DM) have been reported, even though coffee is the most consumed beverage in the world.To determine the relationship between coffee consumption and the incidence of type 2 DM among Finnish individuals, who have the highest coffee consumption in the world.A prospective study from combined surveys conducted in 1982, 1987, and 1992 of 6974 (...) Finnish men and 7655 women aged 35 to 64 years without history of stroke, coronary heart disease, or DM at baseline, with 175 682 person-years of follow-up. Coffee consumption and other study parameters were determined at baseline using standardized measurements.Hazard ratios (HRs) for the incidence of type 2 DM were estimated for different levels of daily coffee consumption.During a mean follow-up of 12 years, there were 381 incident cases of type 2 DM. After adjustment for confounding factors (age

2004 JAMA

1873. Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. Full Text available with Trip Pro

Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. To examine the association of type 2 diabetes with baseline cognitive function and cognitive decline over two years of follow up, focusing on women living in the community and on the effects of treatments for diabetes.Nurses' health study in the United States. Two cognitive interviews were carried out by telephone during 1995-2003.18 999 women aged 70-81 years who had been registered nurses completed (...) the baseline interview; to date, 16 596 participants have completed follow up interviews after two years.Cognitive assessments included telephone interview of cognitive status, immediate and delayed recalls of the East Boston memory test, test of verbal fluency, delayed recall of 10 word list, and digit span backwards. Global scores were calculated by averaging the results of all tests with z scores.After multivariate adjustment, women with type 2 diabetes performed worse on all cognitive tests than women

2004 BMJ

1874. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. Full Text available with Trip Pro

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. Insulin resistance appears to be the best predictor of the development of diabetes in the children of patients with type 2 diabetes, but the mechanism responsible is unknown.We performed hyperinsulinemic-euglycemic clamp studies in combination with infusions of [6,6-(2)H(2)]glucose in healthy, young, lean, insulin-resistant offspring of patients with type 2 diabetes and insulin-sensitive control (...) dysfunction, as reflected by a reduction of approximately 30 percent in mitochondrial phosphorylation (P=0.01 for the comparison with controls), since there were no significant differences in systemic or localized rates of lipolysis or plasma concentrations of tumor necrosis factor alpha, interleukin-6, resistin, or adiponectin.These data support the hypothesis that insulin resistance in the skeletal muscle of insulin-resistant offspring of patients with type 2 diabetes is associated with dysregulation

2004 NEJM

1875. Body iron stores in relation to risk of type 2 diabetes in apparently healthy women. Full Text available with Trip Pro

Body iron stores in relation to risk of type 2 diabetes in apparently healthy women. Type 2 diabetes is a common manifestation of hemochromatosis, a disease of iron overload. However, it is not clear whether higher iron stores predict the development of type 2 diabetes in a healthy population.To examine plasma ferritin concentration and the ratio of the concentrations of transferrin receptors to ferritin in relation to risk of type 2 diabetes.Prospective nested case-control study within (...) the Nurses' Health Study cohort. Of the 32 826 women who provided blood samples during 1989-1990 and were free of diagnosed diabetes, cardiovascular disease, and cancer, 698 developed diabetes during 10 years of follow-up. The controls (n = 716) were matched to cases on age, race, and fasting status; and on body mass index (BMI) for cases in the top BMI decile.Incident cases of type 2 diabetes.Among cases, the mean (SD) concentration of ferritin was significantly higher (109 [105] vs 71.5 [68.7] ng/mL

2004 JAMA

1876. Elevated plasma homocysteine level is an independent predictor of coronary heart disease events in patients with type 2 diabetes mellitus. (Abstract)

Elevated plasma homocysteine level is an independent predictor of coronary heart disease events in patients with type 2 diabetes mellitus. High plasma homocysteine level has been associated with increased risk for coronary heart disease (CHD) events in nondiabetic individuals, especially in those with previously diagnosed CHD. In persons with type 2 diabetes mellitus, the association between homocysteine level and cardiovascular disease may be stronger than that in nondiabetic individuals (...) , but no large prospective studies have examined the relationship between homocysteine level and CHD mortality in persons with type 2 diabetes.To investigate whether moderately elevated plasma homocysteine levels are independently related to increased incidence of fatal and nonfatal CHD events in persons with type 2 diabetes.Prospective study.Finnish sample of patients with type 2 diabetes.462 men and 368 women who were 45 to 64 years of age at baseline.Coronary heart disease mortality and incidence

2004 Annals of Internal Medicine

1877. Coffee consumption and risk for type 2 diabetes mellitus. (Abstract)

Coffee consumption and risk for type 2 diabetes mellitus. In small, short-term studies, acute administration of caffeine decreases insulin sensitivity and impairs glucose tolerance.To examine the long-term relationship between consumption of coffee and other caffeinated beverages and incidence of type 2 diabetes mellitus.Prospective cohort study.The Nurses' Health Study and Health Professionals' Follow-up Study.The authors followed 41 934 men from 1986 to 1998 and 84 276 women from 1980 to 1998 (...) . These participants did not have diabetes, cancer, or cardiovascular disease at baseline.Coffee consumption was assessed every 2 to 4 years through validated questionnaires.The authors documented 1333 new cases of type 2 diabetes in men and 4085 new cases in women. The authors found an inverse association between coffee intake and type 2 diabetes after adjustment for age, body mass index, and other risk factors. The multivariate relative risks for diabetes according to regular coffee consumption categories (0, <1

2004 Annals of Internal Medicine

1878. BPG for the Subcutaneous Administration of Insulin in Adults with Type 2 Diabetes

BPG for the Subcutaneous Administration of Insulin in Adults with Type 2 Diabetes Best Practice Guideline for the Subcutaneous Administration of Insulin in Adults with Type 2 Diabetes Nursing Best Practice Guideline Shaping the future of Nursing June 2004Greetings from Doris Grinspun Executive Director Registered Nurses Association of Ontario It is with great excitement that the Registered Nurses Association of Ontario (RNAO) disseminates this nursing best practice guideline to you. Evidence (...) Administration of Insulin in Adults with Type 2 Diabetes Guideline Development Panel Members Declarations of interest and confidentiality were made by all members of the guideline development panel. Further details are available from the Registered Nurses Association of Ontario. Anna Brundage, RN, BHSc(N), CDE Team Leader Manager TRIDEC Sunnybrook and Women’s College Health Sciences Centre Toronto, Ontario Ceilia Ayotte, RN, CDE Diabetes Educator Peterborough Regional Health Centre Peterborough, Ontario

2004 Registered Nurses' Association of Ontario

1879. Dietary advice for treatment of type 2 diabetes mellitus in adults. Full Text available with Trip Pro

Dietary advice for treatment of type 2 diabetes mellitus in adults. While initial dietary management immediately after formal diagnosis is an 'accepted' cornerstone of treatment of type 2 diabetes mellitus, a formal and systematic overview of its efficacy and method of delivery is not currently available.To assess the effect of type and frequency of different types of dietary advice to all adults with type 2 diabetes on weight, measures of diabetic control, morbidity, total mortality (...) and quality of life.We carried out a comprehensive search of The Cochrane Library (The Cochrane Library Issue 3, 2003), MEDLINE (1966 to October Week 1, 2003), EMBASE (1980 to Week 40, 2003), CINAHL (1982 to October Week 1, 2003), AMED (1985 to October 2003), bibliographies and contacted relevant experts.All randomised controlled trials, of six months or longer, in which dietary advice was the main intervention in adults with type 2 diabetes mellitus.The lead investigator performed all data extraction

2004 Cochrane

1880. Dietary advice for treatment of type 2 diabetes mellitus in adults. Full Text available with Trip Pro

Dietary advice for treatment of type 2 diabetes mellitus in adults. While initial dietary management immediately after formal diagnosis is an 'accepted' cornerstone of treatment of type 2 diabetes mellitus, a formal and systematic overview of its efficacy and method of delivery is not currently available.To assess the effect of type and frequency of different types of dietary advice to all adults with type 2 diabetes on weight, measures of diabetic control, morbidity, total mortality (...) and quality of life.We carried out a comprehensive search of The Cochrane Library (The Cochrane Library Issue 3, 2003), MEDLINE (1966 to October Week 1, 2003), EMBASE (1980 to Week 40, 2003), CINAHL (1982 to October Week 1, 2003), AMED (1985 to October 2003), bibliographies and contacted relevant experts.All randomised controlled trials, of six months or longer, in which dietary advice was the main intervention in adults with type 2 diabetes mellitus.The lead investigator performed all data extraction

2004 Cochrane