Latest & greatest articles for urinary tract infection

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Top results for urinary tract infection

201. Oral versus initial intravenous therapy for urinary tract infections in young febrile children

Oral versus initial intravenous therapy for urinary tract infections in young febrile children Oral versus initial intravenous therapy for urinary tract infections in young febrile children Oral versus initial intravenous therapy for urinary tract infections in young febrile children Hoberman A, Wald E R, Hickey R W, Baskin M, Charron M, Majd M, Kearney D H, Reynolds E A, Ruley J, Janosky J E Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Treatment with oral antibiotics alone was compared with intravenous (i.v.) treatment followed by oral antibiotics for young children with fever and urinary tract infection (UTI). Children receiving i.v. treatment were hospitalised and treated with cefotaxime (Claforan) at a dose

1999 NHS Economic Evaluation Database.

202. Hydrogel/silver ion-coated urinary catheter reduces nosocomial urinary tract infection rates in intensive care unit patients: a multicenter study

Hydrogel/silver ion-coated urinary catheter reduces nosocomial urinary tract infection rates in intensive care unit patients: a multicenter study Hydrogel/silver ion-coated urinary catheter reduces nosocomial urinary tract infection rates in intensive care unit patients: a multicenter study Hydrogel/silver ion-coated urinary catheter reduces nosocomial urinary tract infection rates in intensive care unit patients: a multicenter study Bologna R A, Tu L M, Polansky M, Fraimow H D, Gordon D (...) Foley catheter. The additional cost of the catheter was offset by the reduction in hospitalisations. Synthesis of costs and benefits Not relevant as a cost-consequences analysis was performed. Authors' conclusions The use of the Bardex ion-coated (I.C.) catheter would lead to cost-savings, by reducing the number of nosocomial urinary tract infections (NUTIs), as was demonstrated by one of the institutions studied. CRD COMMENTARY - Selection of comparators The rationale for the choice

1999 NHS Economic Evaluation Database.

203. The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis

The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis Saint S, Elmore J G, Sullivan S D, Emerson S S, Koepsell T D Authors' objectives To answer the question: 'compared with standard non-coated indwelling catheters, are silver (...) -coated urinary catheters less likely to lead to urinary tract infection?' Searching MEDLINE was searched from January 1, 1966, to January 31, 1997, using the exploded keywords 'silver' and 'catheter'. Publications in any language were considered. The references of identified articles were also examined. Additional published and unpublished studies were identified by contacting the original authors of the included trials, catheter manufacturers, and experts in the field. Study selection Study designs

1998 DARE.

204. Evaluation of suspected urinary tract infection in ambulatory women

Evaluation of suspected urinary tract infection in ambulatory women Evaluation of suspected urinary tract infection in ambulatory women Evaluation of suspected urinary tract infection in ambulatory women Barry H C, Ebell M H, Hickner J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability (...) of the study and the conclusions drawn. Health technology Office-based strategies for the management of suspected urinary tract infections (UTI): empiric therapy, use of dipstick and microscopic urinalysis, use of complete urinalysis and use of office or laboratory cultures. Type of intervention Diagnosis and treatment. Economic study type Cost-utility analysis. Study population An otherwise healthy woman aged 18 to 50, who presents to her primary care physician with suspected urinary tract infections

1997 NHS Economic Evaluation Database.

205. Limited vs full microbiological investigation for the management of symptomatic polymicrobial urinary tract infection in adult spinal cord-injured patients

Limited vs full microbiological investigation for the management of symptomatic polymicrobial urinary tract infection in adult spinal cord-injured patients Limited vs full microbiological investigation for the management of symptomatic polymicrobial urinary tract infection in adult spinal cord-injured patients Limited vs full microbiological investigation for the management of symptomatic polymicrobial urinary tract infection in adult spinal cord-injured patients Darouiche R O, Priebe M (...) , Clarridge J E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Limited microbiological investigation of urine culture to guide antibiotic therapy of urinary tract infection (UTI) of patients with spinal cord injury (SCI). Type

1997 NHS Economic Evaluation Database.

206. The cost-effectiveness of placing urinary tract infection treatment over the counter

The cost-effectiveness of placing urinary tract infection treatment over the counter The cost-effectiveness of placing urinary tract infection treatment over the counter The cost-effectiveness of placing urinary tract infection treatment over the counter Rubin N, Foxman B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed (...) critical assessment on the reliability of the study and the conclusions drawn. Health technology Urinary tract infection treatment (UTI) available over-the-counter. Type of intervention Treatment (mode of service delivery). Economic study type Cost-effectiveness analysis. Study population A hypothetical cohort of women with symptoms of UTI. High-risk subpopulations such as diabetics, pregnant women, women with AIDS, and women with structural abnormalities of the urinary tract, were not considered

1996 NHS Economic Evaluation Database.

207. The cost effectiveness of combined rapid tests (Multistix) in screening for urinary tract infections

The cost effectiveness of combined rapid tests (Multistix) in screening for urinary tract infections The cost effectiveness of combined rapid tests (Multistix) in screening for urinary tract infections The cost effectiveness of combined rapid tests (Multistix) in screening for urinary tract infections Fowlis G A, Waters J, Williams G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Use of combined rapid tests (Multistix) in screening for urinary tract infections. Type of intervention Screening. Economic study type Cost-effectiveness analysis. Study population Urology outpatients and renal transplant patients. Setting The economic study was carried out at a hospital in London, UK. Dates to which data relate Not given. Source

1994 NHS Economic Evaluation Database.

208. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. Full Text available with Trip Pro

A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. Recurrent urinary tract infections are a problem for many postmenopausal women. Estrogen replacement restores atrophic mucosa, lowers vaginal pH, and may prevent urinary tract infections.We enrolled 93 postmenopausal women with a history of recurrent urinary tract infections in a randomized, double-blind, placebo-controlled trial of a topically applied intravaginal estriol cream (...) . Midstream urine cultures were obtained at enrollment, monthly for eight months, and whenever urinary symptoms occurred. Vaginal cultures and pH measurements were obtained at entry and after one and eight months. The women were assigned to receive either estriol (n = 50) or placebo (n = 43), both administered intravaginally; 36 and 24, respectively, completed the eight months of follow-up.The incidence of urinary tract infection in the group given estriol was significantly reduced as compared

1993 NEJM Controlled trial quality: predicted high

209. Prophylactic ciprofloxacin for catheter-associated urinary-tract infection. (Abstract)

Prophylactic ciprofloxacin for catheter-associated urinary-tract infection. Patients receiving antibiotics during bladder drainage have a lower incidence of urinary-tract infections compared with similar patients not on antibiotics. However, antibiotic prophylaxis in patients with a urinary catheter is opposed because of the fear of inducing resistant bacterial strains. We have done a double-blind, placebo-controlled trial of prophylactic ciprofloxacin in selected groups of surgical patients (...) % while the catheter was in place; by contrast, the rate of pyuria was 11% or less in patients receiving ciprofloxacin (RR 4.0 [2.1-7.3]). 20% of placebo patients had symptomatic urinary-tract infections, including 3 with septicaemia, compared with 5% of the ciprofloxacin groups (RR 4.0 [1.6-10.2]). Bacteria isolated from urines of placebo patients at catheter removal were mostly species of enterobacteriaceae (37%), staphylococci (26%), and Enterococcus faecalis (20%), whereas species isolated from

1992 Lancet Controlled trial quality: predicted high

210. Postcoital antimicrobial prophylaxis for recurrent urinary tract infection. A randomized, double-blind, placebo-controlled trial. (Abstract)

Postcoital antimicrobial prophylaxis for recurrent urinary tract infection. A randomized, double-blind, placebo-controlled trial. We conducted a randomized, double-blind, placebo-controlled study to determine the efficacy of postcoital antibiotic prophylaxis in healthy young women prone to recurrent urinary tract infections. Sixteen patients were randomized to receive postcoital administration of a combination product of trimethoprim and sulfamethoxazole, while 11 received postcoital placebo (...) . The treatment groups were similar with respect to age, parity, diaphragm use, history of lifetime urinary tract infections, frequency of intercourse, and number of lifetime sexual partners. In over 6 months of observation, postcoital administration of trimethoprim-sulfamethoxazole was highly effective in preventing recurrent urinary tract infections. Nine of 11 patients who took the placebo developed urinary tract infections (infection rate, 3.6 per patient-year), compared with only two of 16 patients who

1990 JAMA Controlled trial quality: uncertain

211. Different lengths of treatment with co-trimoxazole for acute uncomplicated urinary tract infections in women. Full Text available with Trip Pro

Different lengths of treatment with co-trimoxazole for acute uncomplicated urinary tract infections in women. To compare three days' and seven days' treatment with co-trimoxazole in women with acute dysuria, strangury, and urinary frequency or urgency.Randomised double blind placebo controlled trial.General practices in the south east of The Netherlands.327 Non-pregnant female patients aged 12 to 65.161 Women were allocated to three days' treatment (co-trimoxazole 960 mg twice a day), and 166 (...) days' treatment (p = 0.29). In only two patients did adverse effects necessitate stopping treatment.Three days of co-trimoxazole seems to be as effective as a seven days' course for treating acute urinary tract infection in non-pregnant women.

1989 BMJ Controlled trial quality: predicted high

212. Bladder irrigation with povidone-iodine in prevention of urinary-tract infections associated with intermittent urethral catheterisation. (Abstract)

Bladder irrigation with povidone-iodine in prevention of urinary-tract infections associated with intermittent urethral catheterisation. Bladder irrigation with povidone-iodine in the prevention of urinary-tract infections after single or intermittent urethral catheterisation was investigated in a controlled study. In the control group (36 patients) the catheter was removed after urethral catheterisation and emptying of the bladder, and in the trial group (42 patients) 50 ml povidone-iodine 2

1985 Lancet Controlled trial quality: uncertain

213. Aztreonam compared with gentamicin for treatment of serious urinary tract infections. (Abstract)

Aztreonam compared with gentamicin for treatment of serious urinary tract infections. 52 patients with serious urinary tract infections were randomised to receive either aztreonam (35) or gentamicin (17). In the aztreonam group 23 patients had unqualified cures, 6 cures with relapse, and 6 cures with reinfection; the comparable numbers in the gentamicin group were 9, 1, and 4. There were no failures with aztreonam and 3 with gentamicin. The most important determinant of outcome was the presence (...) or absence of urological abnormalities. 11 further patients, with renal failure or gentamicin-resistant isolates, treated with aztreonam were all cured. Toxic effects were limited to symptomless liver-function-test abnormalities with aztreonam , whereas deterioration in renal function occurred in 4 gentamicin-treated subjects. Urinary colonisation with group D streptococci occurred in 14 of 46 aztreonam -treated patients (1 required treatment) compared with only 1 of 17 gentamicin-treated patients. 97

1984 Lancet Controlled trial quality: uncertain

214. Reduction of mortality associated with nosocomial urinary tract infection. (Abstract)

Reduction of mortality associated with nosocomial urinary tract infection. A randomised controlled trial was conducted to assess whether bladder catheters with preconnected sealed junctions were associated with a lower risk of urinary-tract infection than were catheters without such junctions, and to determine whether prevention of catheter-associated infection would be accompanied by a reduction of mortality. Among those not taking systemic antibiotics, patients assigned sealed junction (...) % CI=1.1-10.7, p=0.03). Among patients who received systemic antibiotic the use of sealed catheters did not affect infection rates (RR=0.9, 95% CI=0.5-1.5, p=0.68) or deaths (RR=1.2, 95% CI=0.6-2.2, p=0.62). These data indicate how the rates of infection and mortality can be reduced in hospital. Since the degree of reduction in mortality corresponded with the degree of reduction of infection, measures to prevent catheter-associated nosocomial urinary tract infection should be implemented.

1983 Lancet Controlled trial quality: predicted high

215. Single-dose amoxicillin therapy for urinary tract infection. Multicenter trial using antibody-coated bacteria localization technique. (Abstract)

Single-dose amoxicillin therapy for urinary tract infection. Multicenter trial using antibody-coated bacteria localization technique. Urine specimens from 134 women with acute, uncomplicated urinary tract infection at three medical centers were examined by the antibody-coated bacteria (ACB) assay. Patients with negative assays (suggesting bladder infection alone) were randomized to receive either a single 3-g oral dose of amoxicillin trihydrate or conventional ten-day courses of sulfa (...) -methoxazole-trimethoprim or oral ampicillin sodium. Comparable results were obtained with the three regimens for ACG-negative infection: 90% eradication of the original organism with single-dose amoxicillin, 100% with sulfamethoxazole-trimethoprim, and 96% with ampicillin. The overall incidence of ACB positivity was 32.1%, ranging from 8% to 63% at the three institutions. This difference seemed to be related to the ease of access to medical care: women with easy access having low rates of ACB positivity

1980 JAMA Controlled trial quality: uncertain

216. Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. (Abstract)

Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. Urine specimens from 61 women with symptoms of cystitis who are infected with amoxicillin-sensitive organisms were examined by the antibody-coated bacteria assay. Patients with negative assays were randomized to receive either a single 3-g oral dose of amoxicillin or 10 days of amoxicillin, 250 mg, given by mouth four times per day (conventional therapy (...) ). Patients with positive assays received conventional therapy. All 43 patients without antibody-coated bacteria in the urine, 22 given single-dose therapy and 21 treated conventionally, were cured of their infection. Of 18 patients with antibody-coated bacteria, nine relapsed within one week of completion of conventional therapy. The results of the antibody-coated bacteria assay appear to predict the therapeutic response: both single-dose and conventional amoxicillin therapy are completely successful

1978 NEJM Controlled trial quality: uncertain

217. Antibiotic irrigation and catheter-associated urinary-tract infections. (Abstract)

Antibiotic irrigation and catheter-associated urinary-tract infections. To investigate the efficacy of antibiotic irrigation in preventing catheter-associated urinarytract infection, we carried out a randomized controlled trial of a neomycin-polymyxin irrigant administered through closed urinary catheters. Eighteen of 98 (18 per cent) of the patients not given irrigation became infected, as compared with 14 of 89 (16 per cent) of those given irrigation, yielding a mean daily incidence of 5 per (...) cent in each group. The distribution of organisms and their antibiotic sensitivities differed in the two groups, the organisms from the patients with irrigation being more resistant. Disconnections of the catheter junctions were associated with high rates of infection. The rate of disconnections of the junctions in the group given irrigation was almost twice that of the control group because of the presence of the extra junction on overall infection rate represents the result of two opposing

1978 NEJM Controlled trial quality: uncertain

218. Trimethoprim-sulfamethoxazole vs ampicillin in chronic urinary tract infections. A double-blind multicenter cooperative controlled study. (Abstract)

Trimethoprim-sulfamethoxazole vs ampicillin in chronic urinary tract infections. A double-blind multicenter cooperative controlled study. A multicenter, prospective, double-blind, controlled study was performed to compare the efficacy of trimethoprim-sulfamethoxazole with that of ampicillin in the treatment of chronic urinary tract infections. The incidence of adverse clinical signs and symptoms as well as abnormal laboratory values were comparable in the two treatment groups. This study (...) appears to establish the fact that trimethoprim-sulfamethoxazole is an acceptable alternative to ampicillin for the treatment of chronic urinary tract infections caused by susceptible Escherichia coli.

1975 JAMA Controlled trial quality: uncertain